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GeneiASE: Detection of condition-dependent and static allele-specific expression from RNA-seq data without haplotype information

Allele-specific expression (ASE) is the imbalance in transcription between maternal and paternal alleles at a locus and can be probed in single individuals using massively parallel DNA sequencing technology. Assessing ASE within a single sample provides a static picture of the ASE, but the magnitude...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Edsgärd, Daniel, Iglesias, Maria Jesus, Reilly, Sarah-Jayne, Hamsten, Anders, Tornvall, Per, Odeberg, Jacob, Emanuelsson, Olof
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758070/
https://ncbi.nlm.nih.gov/pubmed/26887787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21134
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