Combined Chromatin and Expression Analysis Reveals Specific Regulatory Mechanisms within Cytokine Genes in the Macrophage Early Immune Response

Macrophages play a critical role in innate immunity, and the expression of early response genes orchestrate much of the initial response of the immune system. Macrophages undergo extensive transcriptional reprogramming in response to inflammatory stimuli such as Lipopolysaccharide (LPS). To identify...

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Autors principals: Jesus Iglesias, Maria, Reilly, Sarah-Jayne, Emanuelsson, Olof, Sennblad, Bengt, Pirmoradian Najafabadi, Mohammad, Folkersen, Lasse, Mälarstig, Anders, Lagergren, Jens, Eriksson, Per, Hamsten, Anders, Odeberg, Jacob
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288078/
https://ncbi.nlm.nih.gov/pubmed/22384210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032306
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