A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease

Amyotrophic lateral sclerosis (ALS) is an aggressive multifactorial disease converging on a common pathology: the degeneration of motor neurons (MNs), their axons and neuromuscular synapses. This vulnerability and dysfunction of MNs highlights the dependency of these large cells on their intracellul...

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Bibliografiska uppgifter
I publikationen:Front Cell Neurosci
Huvudupphovsmän: Clark, Jayden A., Yeaman, Elise J., Blizzard, Catherine A., Chuckowree, Jyoti A., Dickson, Tracey C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2016
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5020100/
https://ncbi.nlm.nih.gov/pubmed/27679561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00204
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