Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells

Tanshinone IIA, one of the most pharmacologically bioactive phytochemicals isolated from Salvia miltiorrhiza Bunge, possesses several biological activities such as anti-inflammation, anti-cancer, neuroprotection and hypolipidemic activities. In this study, we aim to investigate the hypocholesterolem...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Chen, Hung-Chen, Chen, Pei-Yi, Wu, Ming-Jiuan, Tai, Mi-Hsueh, Yen, Jui-Hung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019481/
https://ncbi.nlm.nih.gov/pubmed/27617748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162414
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