Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share common signaling pathways, they are capable of having distinct effects on cellular plasticity. We investigated the individual effects of mGluR...

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Udgivet i:PLoS One
Main Authors: Gross, Kellie S., Brandner, Dieter D., Martinez, Luis A., Olive, M. Foster, Meisel, Robert L., Mermelstein, Paul G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019418/
https://ncbi.nlm.nih.gov/pubmed/27618534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162755
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