Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

The group I metabotropic glutamate receptors (mGluR1a and mGluR5) are important modulators of neuronal structure and function. Although these receptors share common signaling pathways, they are capable of having distinct effects on cellular plasticity. We investigated the individual effects of mGluR...

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Publicat a:PLoS One
Autors principals: Gross, Kellie S., Brandner, Dieter D., Martinez, Luis A., Olive, M. Foster, Meisel, Robert L., Mermelstein, Paul G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019418/
https://ncbi.nlm.nih.gov/pubmed/27618534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162755
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