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Protein kinase Cε activity regulates mGluR5 surface expression in the rat nucleus accumbens

Type 5 metabotropic glutamate receptors (mGluR5) activate protein kinase C (PKC) via coupling to G(αq/11) protein signaling. We have previously demonstrated that the epsilon isoform of PKC (PKCε) is a critical downstream target of mGluR5 in regulating behavioral and biochemical responses to alcohol....

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Detalles Bibliográficos
Publicado en:J Neurosci Res
Main Authors: Schwendt, Marek, Olive, M. Foster
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296288/
https://ncbi.nlm.nih.gov/pubmed/27546836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23868
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