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Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like Growth Factor 1 expression in the brain

The peptide hormones insulin-like growth factor-1 (IGF1) and leptin mediate a myriad of biological effects - both in the peripheral and central nervous systems. The transcription of these two hormones is regulated by the transcription factor C/EBPα, which in turn is negatively regulated by the trans...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Marwarha, Gurdeep, Claycomb, Kate, Schommer, Jared, Collins, David, Ghribi, Othman
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5019029/
https://ncbi.nlm.nih.gov/pubmed/27555288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2016.08.012
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