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Palmitate induced C/EBP homologous protein activation leads to NF-κB -mediated increase in BACE1 activity and Amyloid beta genesis
The etiology of Alzheimer’s disease (AD) is egregiously comprehended, but epidemiological studies have posited that diets rich in the saturated fatty acid palmitic acid (palmitate) are a significant risk factor. The production and accumulation of Amyloid-beta peptide (Aβ) is considered the core path...
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| Pubblicato in: | J Neurochem |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6371812/ https://ncbi.nlm.nih.gov/pubmed/29315574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14292 |
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