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The Mechanism of Hsp90 ATPase Stimulation by Aha1

Hsp90 is a dimeric molecular chaperone responsible for the folding, maturation, and activation of hundreds of substrate proteins called ‘clients’. Numerous co-chaperone proteins regulate progression through the ATP-dependent client activation cycle. The most potent stimulator of the Hsp90 ATPase act...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wolmarans, Annemarie, Lee, Brian, Spyracopoulos, Leo, LaPointe, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018835/
https://ncbi.nlm.nih.gov/pubmed/27615124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33179
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