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The Mechanism of Hsp90 ATPase Stimulation by Aha1

Hsp90 is a dimeric molecular chaperone responsible for the folding, maturation, and activation of hundreds of substrate proteins called ‘clients’. Numerous co-chaperone proteins regulate progression through the ATP-dependent client activation cycle. The most potent stimulator of the Hsp90 ATPase act...

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Publicat a:Sci Rep
Autors principals: Wolmarans, Annemarie, Lee, Brian, Spyracopoulos, Leo, LaPointe, Paul
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018835/
https://ncbi.nlm.nih.gov/pubmed/27615124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33179
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