Binding of EBP50 to Nox organizing subunit p47(phox) is pivotal to cellular reactive species generation and altered vascular phenotype

Despite numerous reports implicating NADPH oxidases (Nox) in the pathogenesis of many diseases, precise regulation of this family of professional reactive oxygen species (ROS) producers remains unclear. A unique member of this family, Nox1 oxidase, functions as either a canonical or hybrid system us...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Al Ghouleh, Imad, Meijles, Daniel N., Mutchler, Stephanie, Zhang, Qiangmin, Sahoo, Sanghamitra, Gorelova, Anastasia, Henrich Amaral, Jefferson, Rodríguez, Andrés I., Mamonova, Tatyana, Song, Gyun Jee, Bisello, Alessandro, Friedman, Peter A., Cifuentes-Pagano, M. Eugenia, Pagano, Patrick J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018796/
https://ncbi.nlm.nih.gov/pubmed/27540115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514161113
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