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Group-combined P-values with applications to genetic association studies
Motivation: In large-scale genetic association studies with tens of hundreds of single nucleotide polymorphisms (SNPs) genotyped, the traditional statistical framework of logistic regression using maximum likelihood estimator (MLE) to infer the odds ratios of SNPs may not work appropriately. This is...
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| Published in: | Bioinformatics |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018368/ https://ncbi.nlm.nih.gov/pubmed/27259542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw314 |
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