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Biomarker-guided heterogeneity analysis of genetic regulations via multivariate sparse fusion

Heterogeneity is a hallmark of many complex diseases. There are multiple ways of defining heterogeneity, among which the heterogeneity in genetic regulations, for example GEs (gene expressions) by CNVs (copy number variations) and methylation, has been suggested but little investigated. Heterogeneit...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Zhang, Sanguo, Hu, Xiaonan, Luo, Ziye, Jiang, Yu, Sun, Yifan, Ma, Shuangge
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8277716/
https://ncbi.nlm.nih.gov/pubmed/33906263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.9006
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