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Characterisation of the epigenetic changes during human gonadal primordial germ cells reprogramming
Epigenetic reprogramming is a central component of the mammalian germline development. Genome-wide DNA demethylation observed in primordial germ cells (PGCs) is a prerequisite for erasure of epigenetic memory, preventing the transmission of epimutations to the next generation. Apart from DNA demethy...
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| Опубликовано в: : | Stem Cells |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5018215/ https://ncbi.nlm.nih.gov/pubmed/27300161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2422 |
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