Environmentally Induced Transgenerational Epigenetic Reprogramming of Primordial Germ Cells and the Subsequent Germ Line

A number of environmental factors (e.g. toxicants) have been shown to promote the epigenetic transgenerational inheritance of disease and phenotypic variation. Transgenerational inheritance requires the germline transmission of altered epigenetic information between generations in the absence of dir...

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Bibliographic Details
Main Authors: Skinner, Michael K., Haque, Carlos Guerrero-Bosagna M., Nilsson, Eric, Bhandari, Ramji, McCarrey, John R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712023/
https://ncbi.nlm.nih.gov/pubmed/23869203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066318
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