Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing Sarcoma

Metastatic Ewing sarcoma has a very poor prognosis and therefore new investigations into the biologic drivers of metastatic progression are key to finding new therapeutic approaches. The tumor microenvironment is highly dynamic, leading to exposure of different regions of a growing solid tumor to ch...

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Udgivet i:Neoplasia
Main Authors: Bailey, Kelly M., Airik, Merlin, Krook, Melanie A., Pedersen, Elisabeth A., Lawlor, Elizabeth R.
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018098/
https://ncbi.nlm.nih.gov/pubmed/27566104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2016.06.008
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