Minimal asbestos exposure in germline BAP1 heterozygous mice is associated with deregulated inflammatory response and increased risk of mesothelioma

Germline BAP1 mutations predispose to several cancers, in particular malignant mesothelioma. Mesothelioma is an aggressive malignancy generally associated to professional exposure to asbestos. However, to date we found that none of the mesothelioma patients carrying germline BAP1 mutations were prof...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Napolitano, A, Pellegrini, L, Dey, A, Larson, D, Tanji, M, Flores, EG, Kendrick, B, Lapid, D, Powers, A, Kanodia, S, Pastorino, S, Pass, HI, Dixit, V, Yang, H, Carbone, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018040/
https://ncbi.nlm.nih.gov/pubmed/26119930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.243
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