High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

BACKGROUND: BAP1 is a nuclear deubiquitinase that regulates gene expression, transcription, DNA repair, and more. Several findings underscore the apparent “driver” role of BAP1 in malignant mesothelioma (MM). However the reported frequency of somatic BAP1 mutations in MM varies considerably, a discr...

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Bibliografiska uppgifter
I publikationen:J Thorac Oncol
Huvudupphovsmän: Nasu, Masaki, Emi, Mitsuru, Pastorino, Sandra, Tanji, Mika, Powers, Amy, Luk, Hugh, Baumann, Francine, Zhang, Yu-an, Gazdar, Adi, Kanodia, Shreya, Tiirikainen, Maarit, Flores, Erin, Gaudino, Giovanni, Becich, Michael J., Pass, Harvey I., Yang, Haining, Carbone, Michele
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408084/
https://ncbi.nlm.nih.gov/pubmed/25658628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000471
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