High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

BACKGROUND: BAP1 is a nuclear deubiquitinase that regulates gene expression, transcription, DNA repair, and more. Several findings underscore the apparent “driver” role of BAP1 in malignant mesothelioma (MM). However the reported frequency of somatic BAP1 mutations in MM varies considerably, a discr...

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書誌詳細
出版年:J Thorac Oncol
主要な著者: Nasu, Masaki, Emi, Mitsuru, Pastorino, Sandra, Tanji, Mika, Powers, Amy, Luk, Hugh, Baumann, Francine, Zhang, Yu-an, Gazdar, Adi, Kanodia, Shreya, Tiirikainen, Maarit, Flores, Erin, Gaudino, Giovanni, Becich, Michael J., Pass, Harvey I., Yang, Haining, Carbone, Michele
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408084/
https://ncbi.nlm.nih.gov/pubmed/25658628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000471
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