High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

BACKGROUND: BAP1 is a nuclear deubiquitinase that regulates gene expression, transcription, DNA repair, and more. Several findings underscore the apparent “driver” role of BAP1 in malignant mesothelioma (MM). However the reported frequency of somatic BAP1 mutations in MM varies considerably, a discr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Thorac Oncol
Prif Awduron: Nasu, Masaki, Emi, Mitsuru, Pastorino, Sandra, Tanji, Mika, Powers, Amy, Luk, Hugh, Baumann, Francine, Zhang, Yu-an, Gazdar, Adi, Kanodia, Shreya, Tiirikainen, Maarit, Flores, Erin, Gaudino, Giovanni, Becich, Michael J., Pass, Harvey I., Yang, Haining, Carbone, Michele
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408084/
https://ncbi.nlm.nih.gov/pubmed/25658628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000471
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