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High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma
BACKGROUND: BAP1 is a nuclear deubiquitinase that regulates gene expression, transcription, DNA repair, and more. Several findings underscore the apparent “driver” role of BAP1 in malignant mesothelioma (MM). However the reported frequency of somatic BAP1 mutations in MM varies considerably, a discr...
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| 出版年: | J Thorac Oncol |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408084/ https://ncbi.nlm.nih.gov/pubmed/25658628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000471 |
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