High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma

BACKGROUND: BAP1 is a nuclear deubiquitinase that regulates gene expression, transcription, DNA repair, and more. Several findings underscore the apparent “driver” role of BAP1 in malignant mesothelioma (MM). However the reported frequency of somatic BAP1 mutations in MM varies considerably, a discr...

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Dades bibliogràfiques
Publicat a:J Thorac Oncol
Autors principals: Nasu, Masaki, Emi, Mitsuru, Pastorino, Sandra, Tanji, Mika, Powers, Amy, Luk, Hugh, Baumann, Francine, Zhang, Yu-an, Gazdar, Adi, Kanodia, Shreya, Tiirikainen, Maarit, Flores, Erin, Gaudino, Giovanni, Becich, Michael J., Pass, Harvey I., Yang, Haining, Carbone, Michele
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408084/
https://ncbi.nlm.nih.gov/pubmed/25658628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000471
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