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High Incidence of Somatic BAP1 Alterations in Sporadic Malignant Mesothelioma
BACKGROUND: BAP1 is a nuclear deubiquitinase that regulates gene expression, transcription, DNA repair, and more. Several findings underscore the apparent “driver” role of BAP1 in malignant mesothelioma (MM). However the reported frequency of somatic BAP1 mutations in MM varies considerably, a discr...
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| Publicat a: | J Thorac Oncol |
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| Autors principals: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408084/ https://ncbi.nlm.nih.gov/pubmed/25658628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000471 |
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