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NF45 functions as an IRES trans-acting factor that is required for translation of cIAP1 during the unfolded protein response

Expression of the cellular inhibitor of apoptosis protein 1 (cIAP1) is unexpectedly repressed at the level of translation under normal physiological conditions in many cell lines. We have previously shown that the 5′ untranslated region of cIAP1 mRNA contains a stress-inducible internal ribosome ent...

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Vydáno v:Cell Death Differ
Hlavní autoři: Graber, TE, Baird, SD, Kao, PN, Mathews, MB, Holcik, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017871/
https://ncbi.nlm.nih.gov/pubmed/19893574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.164
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