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Peroral Estradiol Is Sufficient to Induce Carcinogen-Induced Mammary Tumorigenesis in Ovariectomized Rats without Progesterone

A role for estrogens in breast cancer is widely accepted, however, recent evidence highlights that timing and exposure levels are important in determining whether they elicit harmful versus beneficial effects. The rat chemical carcinogen model has been widely used to study the effects of estrogens b...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Stires, Hillary, Saboya, Mariana, Globerman, Samantha P., Cohick, Wendie S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017759/
https://ncbi.nlm.nih.gov/pubmed/27611094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162662
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