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Raloxifene and/or estradiol decrease anxiety-like and depressive-like behavior, whereas only estradiol increases carcinogen-induced tumorigenesis and uterine proliferation among ovariectomized rats

Controversy surrounds the efficacy and safety of 17β-estradiol (E(2))-mimetic therapies to women for treatment of menopausal symptoms. An important question is the nature of the trophic actions of E(2)-mimetics in the brain for behavioral processes versus in the periphery for beneficial effects rela...

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Autori principali: Walf, Alicia A., Frye, Cheryl A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885355/
https://ncbi.nlm.nih.gov/pubmed/20480545
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