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Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity

Replicative DNA helicases expose the two strands of the double helix to the replication apparatus, but accessory helicases are often needed to help forks move past naturally occurring hard-to-replicate sites, such as tightly bound proteins, RNA/DNA hybrids, and DNA secondary structures. Although the...

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書目詳細資料
發表在:PLoS Genet
Main Authors: McDonald, Karin R., Guise, Amanda J., Pourbozorgi-Langroudi, Parham, Cristea, Ileana M., Zakian, Virginia A., Capra, John A., Sabouri, Nasim
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017727/
https://ncbi.nlm.nih.gov/pubmed/27611590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006238
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