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Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity

Replicative DNA helicases expose the two strands of the double helix to the replication apparatus, but accessory helicases are often needed to help forks move past naturally occurring hard-to-replicate sites, such as tightly bound proteins, RNA/DNA hybrids, and DNA secondary structures. Although the...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS Genet
Main Authors: McDonald, Karin R., Guise, Amanda J., Pourbozorgi-Langroudi, Parham, Cristea, Ileana M., Zakian, Virginia A., Capra, John A., Sabouri, Nasim
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017727/
https://ncbi.nlm.nih.gov/pubmed/27611590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006238
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