Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity

Replicative DNA helicases expose the two strands of the double helix to the replication apparatus, but accessory helicases are often needed to help forks move past naturally occurring hard-to-replicate sites, such as tightly bound proteins, RNA/DNA hybrids, and DNA secondary structures. Although the...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: McDonald, Karin R., Guise, Amanda J., Pourbozorgi-Langroudi, Parham, Cristea, Ileana M., Zakian, Virginia A., Capra, John A., Sabouri, Nasim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017727/
https://ncbi.nlm.nih.gov/pubmed/27611590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006238
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