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Contemporary Pharyngeal and Invasive emm1 and Invasive emm12 Group A Streptococcus Isolates Exhibit Similar In Vivo Selection for CovRS Mutants in Mice

Group A Streptococcus (GAS) causes diverse infections ranging from common pharyngitis to rare severe invasive infections. Invasive GAS isolates can have natural mutations in the virulence regulator CovRS, which result in enhanced expression of multiple virulence genes, suppressed the expression of t...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Feng, Wenchao, Liu, Mengyao, Chen, Daniel G., Yiu, Rossana, Fang, Ferric C., Lei, Benfang
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017694/
https://ncbi.nlm.nih.gov/pubmed/27611332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162742
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