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Hypervirulent Group A Streptococcus of Genotype emm3 Invades the Vascular System in Pulmonary Infection of Mice

Natural mutations of the two-component regulatory system CovRS are frequently associated with invasive group A Streptococcus (GAS) isolates and lead to the enhancement of virulence gene expression, innate immune evasion, systemic dissemination, and virulence. How CovRS mutations enhance systemic dis...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Lei, Benfang, Minor, Dylan, Feng, Wenchao, Liu, Mengyao
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5964506/
https://ncbi.nlm.nih.gov/pubmed/29610254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00080-18
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