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Genetic variants in Alzheimer disease – molecular and brain network approaches

Genetic studies in late-onset Alzheimer disease (LOAD) are aimed at identifying core disease mechanisms and providing potential biomarkers and drug candidates to improve clinical care for AD. However, due to the complexity of LOAD, including pathological heterogeneity and disease polygenicity, extra...

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Podrobná bibliografie
Vydáno v:Nat Rev Neurol
Hlavní autoři: Gaiteri, Chris, Mostafavi, Sara, Honey, Christopher, De Jager, Philip L., Bennett, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017598/
https://ncbi.nlm.nih.gov/pubmed/27282653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2016.84
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