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Exonuclease of Human DNA Polymerase Gamma Disengages its Strand Displacement Function

Pol γ, the only DNA repair and replication. During mtDNA base-excision repair, gaps are created after damaged base excision. Here we show that Pol γ efficiently gap-fills except when the gap is only a single nucleotide. Although wild-type Pol γ has very limited ability for strand displacement DNA sy...

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Detalhes bibliográficos
Publicado no:Mitochondrion
Main Authors: He, Quan, Shumate, Christie K., White, Mark A, Molineux, Ian J., Yin, Y. Whitney
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017585/
https://ncbi.nlm.nih.gov/pubmed/23993955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2013.08.003
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