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Hedgehog signal transduction: key players, oncogenic drivers, and cancer therapy
The Hedgehog (Hh) signaling pathway governs complex developmental processes, including proliferation and patterning within diverse tissues. These activities rely on a tightly-regulated transduction system that converts graded Hh input signals into specific levels of pathway activity. Uncontrolled ac...
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| Publicado no: | Dev Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5017307/ https://ncbi.nlm.nih.gov/pubmed/27554855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.07.026 |
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