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Hedgehog signal transduction: key players, oncogenic drivers, and cancer therapy

The Hedgehog (Hh) signaling pathway governs complex developmental processes, including proliferation and patterning within diverse tissues. These activities rely on a tightly-regulated transduction system that converts graded Hh input signals into specific levels of pathway activity. Uncontrolled ac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Cell
Prif Awduron: Pak, Ekaterina, Segal, Rosalind A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017307/
https://ncbi.nlm.nih.gov/pubmed/27554855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.07.026
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