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Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapy

The HEDGEHOG-GLI (HH-GLI) signalling is a key pathway critical in embryonic development, stem cell biology and tissue homeostasis. In recent years, aberrant activation of HH-GLI signalling has been linked to several types of cancer, including those of the skin, brain, lungs, prostate, gastrointestin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Expert Rev Mol Med
Hauptverfasser: Pandolfi, Silvia, Stecca, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cambridge University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836208/
https://ncbi.nlm.nih.gov/pubmed/25660620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/erm.2015.3
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