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Optimized Protocol To Analyze Changes in the Lipidome of Xenografts after Treatment with 2-Hydroxyoleic Acid

Xenografts are a popular model for the study of the action of new antitumor drugs. However, xenografts are highly heterogeneous structures, and therefore it is sometimes difficult to evaluate the effects of the compounds on tumor metabolism. In this context, imaging mass spectrometry (IMS) may yield...

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Publicado en:Anal Chem
Main Authors: Fernández, Roberto, Garate, Jone, Lage, Sergio, Terés, Silvia, Higuera, Mónica, Bestard-Escalas, Joan, Martin, M. Laura, López, Daniel H., Guardiola-Serrano, Francisca, Escribá, Pablo V., Barceló-Coblijn, Gwendolyn, Fernández, José A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017204/
https://ncbi.nlm.nih.gov/pubmed/26607740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b03978
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