Two-photon polymerized “nichoid” substrates maintain function of pluripotent stem cells when expanded under feeder-free conditions

BACKGROUND: The use of pluripotent cells in stem cell therapy has major limitations, mainly related to the high costs and risks of exogenous conditioning and the use of feeder layers during cell expansion passages. METHODS: We developed an innovative three-dimensional culture substrate made of “nich...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Nava, Michele M., Piuma, Alessio, Figliuzzi, Marina, Cattaneo, Irene, Bonandrini, Barbara, Zandrini, Tommaso, Cerullo, Giulio, Osellame, Roberto, Remuzzi, Andrea, Raimondi, Manuela T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016857/
https://ncbi.nlm.nih.gov/pubmed/27613598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0387-z
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