Two-photon polymerized “nichoid” substrates maintain function of pluripotent stem cells when expanded under feeder-free conditions

BACKGROUND: The use of pluripotent cells in stem cell therapy has major limitations, mainly related to the high costs and risks of exogenous conditioning and the use of feeder layers during cell expansion passages. METHODS: We developed an innovative three-dimensional culture substrate made of “nich...

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Bibliographic Details
Published in:Stem Cell Res Ther
Main Authors: Nava, Michele M., Piuma, Alessio, Figliuzzi, Marina, Cattaneo, Irene, Bonandrini, Barbara, Zandrini, Tommaso, Cerullo, Giulio, Osellame, Roberto, Remuzzi, Andrea, Raimondi, Manuela T.
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016857/
https://ncbi.nlm.nih.gov/pubmed/27613598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0387-z
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