Two-photon polymerized “nichoid” substrates maintain function of pluripotent stem cells when expanded under feeder-free conditions

BACKGROUND: The use of pluripotent cells in stem cell therapy has major limitations, mainly related to the high costs and risks of exogenous conditioning and the use of feeder layers during cell expansion passages. METHODS: We developed an innovative three-dimensional culture substrate made of “nich...

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發表在:Stem Cell Res Ther
Main Authors: Nava, Michele M., Piuma, Alessio, Figliuzzi, Marina, Cattaneo, Irene, Bonandrini, Barbara, Zandrini, Tommaso, Cerullo, Giulio, Osellame, Roberto, Remuzzi, Andrea, Raimondi, Manuela T.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016857/
https://ncbi.nlm.nih.gov/pubmed/27613598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0387-z
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