Two-photon polymerized “nichoid” substrates maintain function of pluripotent stem cells when expanded under feeder-free conditions

BACKGROUND: The use of pluripotent cells in stem cell therapy has major limitations, mainly related to the high costs and risks of exogenous conditioning and the use of feeder layers during cell expansion passages. METHODS: We developed an innovative three-dimensional culture substrate made of “nich...

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Detalles Bibliográficos
Publicado en:Stem Cell Res Ther
Main Authors: Nava, Michele M., Piuma, Alessio, Figliuzzi, Marina, Cattaneo, Irene, Bonandrini, Barbara, Zandrini, Tommaso, Cerullo, Giulio, Osellame, Roberto, Remuzzi, Andrea, Raimondi, Manuela T.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016857/
https://ncbi.nlm.nih.gov/pubmed/27613598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-016-0387-z
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