Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines

Oxaliplatin displays a wide spectrum of antitumor activities and is widely used in the treatment of metastatic colorectal cancer (CRC). However, tumor responses to this agent are variable, and the underlying mechanisms are poorly understood. In the present study, oxaliplatin was found to strongly in...

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Publicado no:Sci Rep
Main Authors: Yang, Chao, Zhou, Qian, Li, Minle, Tong, Xuemei, Sun, Jiayi, Qing, Yin, Sun, Liya, Yang, Xuhan, Hu, Xiaowen, Jiang, Jie, Yan, Xiaomei, He, Lin, Wan, Chunling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016804/
https://ncbi.nlm.nih.gov/pubmed/27609465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33078
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