Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines

Oxaliplatin displays a wide spectrum of antitumor activities and is widely used in the treatment of metastatic colorectal cancer (CRC). However, tumor responses to this agent are variable, and the underlying mechanisms are poorly understood. In the present study, oxaliplatin was found to strongly in...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Yang, Chao, Zhou, Qian, Li, Minle, Tong, Xuemei, Sun, Jiayi, Qing, Yin, Sun, Liya, Yang, Xuhan, Hu, Xiaowen, Jiang, Jie, Yan, Xiaomei, He, Lin, Wan, Chunling
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016804/
https://ncbi.nlm.nih.gov/pubmed/27609465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33078
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items