KIF11 is upregulated in colorectal cancer and silencing of it impairs tumor growth and sensitizes colorectal cancer cells to oxaliplatin via p53/GSK3β signaling

Colorectal cancer (CRC) is the most frequently diagnosed cancer of the digestive tract. Chemotherapy drugs such as oxaliplatin are frequently administered to CRC patients diagnosed with advanced or metastatic disease. A deep understanding of the molecular mechanism underlying CRC tumorigenesis and i...

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Bibliographische Detailangaben
Veröffentlicht in:J Cancer
Hauptverfasser: Zhou, Yan, Yang, Leping, Xiong, Li, Wang, Kunpeng, Hou, Xuyang, Li, Qinglong, Kong, Fanhua, Liu, Xi, He, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120193/
https://ncbi.nlm.nih.gov/pubmed/33995648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.52103
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