KIF11 is upregulated in colorectal cancer and silencing of it impairs tumor growth and sensitizes colorectal cancer cells to oxaliplatin via p53/GSK3β signaling

Colorectal cancer (CRC) is the most frequently diagnosed cancer of the digestive tract. Chemotherapy drugs such as oxaliplatin are frequently administered to CRC patients diagnosed with advanced or metastatic disease. A deep understanding of the molecular mechanism underlying CRC tumorigenesis and i...

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Publicado en:J Cancer
Autores principales: Zhou, Yan, Yang, Leping, Xiong, Li, Wang, Kunpeng, Hou, Xuyang, Li, Qinglong, Kong, Fanhua, Liu, Xi, He, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120193/
https://ncbi.nlm.nih.gov/pubmed/33995648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.52103
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