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Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death

Glucocorticoid receptor (GR) signaling has recently been shown to play a direct role in the regulation of cardiomyocyte function. In this study, we investigated the potential role of KLF13 as a downstream effector of GR action utilizing both in vivo and in vitro approaches. Our data show that KLF13...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cruz-Topete, Diana, He, Bo, Xu, Xiaojiang, Cidlowski, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016677/
https://ncbi.nlm.nih.gov/pubmed/27451392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.725903
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