Cardiomyocyte glucocorticoid and mineralocorticoid receptors directly and antagonistically regulate heart disease in mice

Stress is increasingly associated with heart dysfunction and is linked to higher mortality rates in patients with cardiometabolic disease. Glucocorticoids are primary stress hormones that regulate homeostasis through two nuclear receptors, the glucocorticoid receptor (GR) and mineralocorticoid recep...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Signal
Prif Awduron: Oakley, Robert H., Cruz-Topete, Diana, He, Bo, Foley, Julie F., Myers, Page H., Xu, Xiaojiang, Gomez-Sanchez, Celso E., Chambon, Pierre, Willis, Monte S., Cidlowski, John A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082727/
https://ncbi.nlm.nih.gov/pubmed/30992401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau9685
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