Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure

BACKGROUND: The contribution of glucocorticoids to sexual dimorphism in the heart is essentially unknown. Therefore, we sought to determine the sexually dimorphic actions of glucocorticoid signaling in cardiac function and gene expression. To accomplish this goal, we conducted studies on mice lackin...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Cruz‐Topete, Diana, Oakley, Robert H., Carroll, Natalie G., He, Bo, Myers, Page H., Xu, Xiaojiang, Watts, Megan N., Trosclair, Krystle, Glasscock, Edward, Dominic, Paari, Cidlowski, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761632/
https://ncbi.nlm.nih.gov/pubmed/31311395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.011012
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