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Identification of a Membrane-bound Prepore Species Clarifies the Lytic Mechanism of Actinoporins
Pore-forming toxins (PFTs) are cytolytic proteins belonging to the molecular warfare apparatus of living organisms. The assembly of the functional transmembrane pore requires several intermediate steps ranging from a water-soluble monomeric species to the multimeric ensemble inserted in the cell mem...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016661/ https://ncbi.nlm.nih.gov/pubmed/27445331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734053 |
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