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A Pore-Forming Toxin Requires a Specific Residue for Its Activity in Membranes with Particular Physicochemical Properties

The physicochemical landscape of the bilayer modulates membrane protein function. Actinoporins are a family of potent hemolytic proteins from sea anemones acting at the membrane level. This family of cytolysins preferentially binds to target membranes containing sphingomyelin, where they form lytic...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Morante, Koldo, Caaveiro, Jose M. M., Tanaka, Koji, González-Mañas, Juan Manuel, Tsumoto, Kouhei
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409249/
https://ncbi.nlm.nih.gov/pubmed/25759390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.615211
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