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In-Cell Enzymology to Probe His-Heme Ligation in Heme Oxygenase Catalysis(,)
Heme oxygenase (HO) is a ubiquitous enzyme with key roles in inflammation, cell signaling, heme disposal, and iron acquisition. HO catalyzes the oxidative conversion of heme to biliverdin (BV) using a conserved histidine to coordinate the iron atom of bound heme. This His-heme interaction has been r...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007156/ https://ncbi.nlm.nih.gov/pubmed/27490825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00562 |
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