Cryopreserved MSCs are susceptible to T-cell mediated apoptosis which is partly rescued by IFNγ licensing

We have previously demonstrated that cryopreservation and thawing lead to altered MSC functionalities. Here, we further analyzed MSC's fitness post freeze-thaw. We have observed that thawed MSC can suppress T-cell proliferation when separated from them by transwell membrane and the effect is lo...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Chinnadurai, Raghavan, Copland, Ian B, Garcia, Marco A, Petersen, Christopher T, Lewis, Christopher N, Waller, Edmund K, Kirk, Allan D, Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016228/
https://ncbi.nlm.nih.gov/pubmed/27299362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2415
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