Immune dysfunctionality of replicative senescent mesenchymal stromal cells is corrected by IFNγ priming

Industrial-scale expansion of mesenchymal stromal cells (MSCs) is often used in clinical trials, and the effect of replicative senescence on MSC functionality is of mechanistic interest. Senescent MSCs exhibit cell-cycle arrest, cellular hypertrophy, and express the senescent marker β-galactosidase....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Chinnadurai, Raghavan, Rajan, Devi, Ng, Spencer, McCullough, Kenneth, Arafat, Dalia, Waller, Edmund K., Anderson, Larry J., Gibson, Greg, Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507374/
https://ncbi.nlm.nih.gov/pubmed/28713871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017006205
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados