Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy

Autologous bone marrow-derived mesenchymal stromal cells (MSCs) for adoptive cell therapy of luminal Crohn's disease (CD) are being tested in clinical trials. However, CD is associated with dysregulation of autophagy and its effect on MSC's immunobiology is unknown. Here, we demonstrate no...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Chinnadurai, Raghavan, Copland, Ian B, Ng, Spencer, Garcia, Marco, Prasad, Mahadev, Arafat, Dalia, Gibson, Greg, Kugathasan, Subra, Galipeau, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817795/
https://ncbi.nlm.nih.gov/pubmed/25899824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.67
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados