Identification of Plant-derived Alkaloids with Therapeutic Potential for Myotonic Dystrophy Type I

Myotonic dystrophy type I (DM1) is a disabling neuromuscular disease with no causal treatment available. This disease is caused by expanded CTG trinucleotide repeats in the 3′ UTR of the dystrophia myotonica protein kinase gene. On the RNA level, expanded (CUG)(n) repeats form hairpin structures tha...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Herrendorff, Ruben, Faleschini, Maria Teresa, Stiefvater, Adeline, Erne, Beat, Wiktorowicz, Tatiana, Kern, Frances, Hamburger, Matthias, Potterat, Olivier, Kinter, Jochen, Sinnreich, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016119/
https://ncbi.nlm.nih.gov/pubmed/27298317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710616
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