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Identification of Plant-derived Alkaloids with Therapeutic Potential for Myotonic Dystrophy Type I
Myotonic dystrophy type I (DM1) is a disabling neuromuscular disease with no causal treatment available. This disease is caused by expanded CTG trinucleotide repeats in the 3′ UTR of the dystrophia myotonica protein kinase gene. On the RNA level, expanded (CUG)(n) repeats form hairpin structures tha...
Gorde:
| Argitaratua izan da: | J Biol Chem |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5016119/ https://ncbi.nlm.nih.gov/pubmed/27298317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710616 |
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