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Structural Features and Functional Dependency on β-Clamp Define Distinct Subfamilies of Bacterial Mismatch Repair Endonuclease MutL

In early reactions of DNA mismatch repair, MutS recognizes mismatched bases and activates MutL endonuclease to incise the error-containing strand of the duplex. DNA sliding clamp is responsible for directing the MutL-dependent nicking to the newly synthesized/error-containing strand. In Bacillus sub...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fukui, Kenji, Baba, Seiki, Kumasaka, Takashi, Yano, Takato
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016104/
https://ncbi.nlm.nih.gov/pubmed/27369079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.739664
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