Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes

We previously reported that overexpression of catalase upregulated xenobiotic- metabolizing enzyme (XME) expression and diminished benzo(a)pyrene (BaP) intermediate accumulation in mouse aortic endothelial cells (MAECs). Endoplasmic reticulum (ER) is the most active organelle involved in BaP metabol...

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Udgivet i:PLoS One
Main Authors: Yang, Fang, Yang, Hong, Ramesh, Aramandla, Goodwin, J. Shawn, Okoro, Emmanuel U., Guo, ZhongMao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015903/
https://ncbi.nlm.nih.gov/pubmed/27607467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162561
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