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Overexpression of Catalase Enhances Benzo(a)pyrene Detoxification in Endothelial Microsomes
We previously reported that overexpression of catalase upregulated xenobiotic- metabolizing enzyme (XME) expression and diminished benzo(a)pyrene (BaP) intermediate accumulation in mouse aortic endothelial cells (MAECs). Endoplasmic reticulum (ER) is the most active organelle involved in BaP metabol...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5015903/ https://ncbi.nlm.nih.gov/pubmed/27607467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162561 |
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